SPCG
Scandinavian Prostate Cancer Group
A research organisation working with clinical trials for progression of the prostate cancer care.
Trials
Our clinical studies
Read about our projects
In the first two decades of the new millennium, there has been a increasing understanding of diagnosis, treatment and prognosis. The results of the SPCG-trials will be presented at this homepage with the goal to give you a good overview of the ongoing studies and updated information of the results.
Recruting/Active
Two randomized clinical trials are recruting patients. The SPCG-15 study is randomizing locally advanced prostate cancer to either radiotherapy or surgery. The second trial recruting patients is the SPCG-19 trial of immediate curative therapy compared with standard conservative treatment in older men with non-metastatic, high-risk prostate cancer. SPCG17 stopped recruiting in 2024. The first analyses are expected in 2026/27.
See trialsFinished
Finished SPCG-trials include for example randomization between surgery and watchful waiting (SPCG-4), the addition of radiotherapy to androgen deprivation therapy in locally advance prostate cancer (SPCG-7), adjuvant docetaxel in addition to surgery (SPCG-12) and radiotherapy (SPCG-13) respectively. Please find more about all the trials at our homepage.
See trialsPublications
Trial summaries
99 publications in total
Here you find the updated publications from the SPCG-trials
Quality of Life after Radical Prostatectomy or Watchful Waiting With or Without Androgen Deprivation Therapy: The SPCG-4 Randomized Trial
Eva Johansson, Gunnar Steineck, Lars Holmberg, Jan-Erik Johansson, Tommy Nyberg, Anna Bill-Axelson; SPCG-4 Investigators
Eur Urol Oncol . 2018
SPCG-4PCASTt/SPCG-17-a randomised trial of active surveillance in prostate cancer: rationale and design
Mats Steinholtz Ahlberg, Hans-Olov Adami, Kerri Beckmann, Helena Bertilsson, Ola Bratt, Declan Cahill, Lars Egevad, Hans Garmo, Lars Holmberg, Eva Johansson, Antti Rannikko, Mieke Van Hemelrijck, Fredrik Jäderling, Cecilia Wassberg, Ulrika W N Åberg, Anna Bill-Axelson
SPCG-17Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts
Kate Tilling, Hans Garmo, Chris Metcalfe, Lars Holmberg, Freddie C Hamdy, David E Neal, Jan Adolfsson, Richard M Martin, Michael Davis, Katja Fall, J Athene Lane, Hans-Olaf Adami, Anna Bill-Axelson, Jan-Eric Johansson, Jenny L Donovan
Eur Urol . 2010
SPCG-4Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial
Eva Johansson, Gunnar Steineck, Lars Holmberg, Jan-Erik Johansson, Tommy Nyberg, Mirja Ruutu, Anna Bill-Axelson; SPCG-4 Investigators
Lancet Oncol . 2011
SPCG-4Individualized estimation of the benefit of radical prostatectomy from the Scandinavian Prostate Cancer Group randomized trial
Andrew Vickers, Caroline Bennette, Gunnar Steineck, Hans-Olov Adami, Jan-Erik Johansson, Anna Bill-Axelson, Juni Palmgren, Hans Garmo, Lars Holmberg
Eur Urol . 2012
SPCG-4
To help you in your daily work, the SPCG welcomes you to our website for further information. You may find important news from the SPCG, updated results of our protocols, abstracts from meetings, information about forthcoming meetings and published clinical research. Important links to other pages related to prostate cancer are included. We hope you will find these pages useful and informative.