Our clinical studies

Read about our projects

In the first two decades of the new millennium there has been a increasing understanding of diagnosis, treatment and prognosis. The results of the SPCG-trials will be presented at this homepage with the goal to give you a good overview of the ongoing studies and updated information of the results.


Two randomized clinical trials are stil including patients. The SPCG-15 study is randomizing locally advanced prostate cancer to either radiotherapy or surgery. The second trial including patients is the SPCG-17 randomized trial of active surveillance including one arm with standardized triggers for curative treatment versus a control arm with clinical practice. The SPCG-14 stoped inclusion 2018 and the first results are analyzed.

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Finished SPCG-trials include for example randomization between surgery and watchful waiting (SPCG-4), the addition of radiotherapy to androgen deprivation therapy in locally advance prostate cancer (SPCG-7), adjuvant docetaxel in addition to surgery (SPCG-12) and radiotherapy (SPCG-13) respectively. Pleas find more about all the trials at our homepage.

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Trial summaries

78 publications in total

Here you find the updated publications from the SPCG-trials


Ten-year survival after High-Dose-Rate Brachytherapy combined with External Beam Radiation Therapy in high-risk prostate cancer: A comparison with the Norwegian SPCG-7 cohort.

Wedde TB, Småstuen MC, Brabrand S, Fosså SD, Kaasa S, Tafjord G, Russnes KM, Hellebust TP, Lilleby W.

Radiother Oncol. 2019


Radical Prostatectomy or Watchful Waiting in Prostate Cancer — 29-Year Follow-up

Bill-Axelson A, Holmberg L, Garmo H, Taari K, Busch C, Nordling S, Häggman M, Andersson SO, Andrén O, Steineck G, Adami HO, Johansson JE.

N Engl J Med. 2018


SPCG-15: a prospective randomized study comparing primary radical prostatectomy and primary radiotherapy plus androgen deprivation therapy for locally advanced prostate cancer.

Stranne J, Brasso K, Brennhovd B, Johansson E, Jäderling F, Kouri M, Lilleby W, Meidahl Petersen P, Mirtti T, Pettersson A, Rannikko A, Thellenberg C, Akre O.

Scand J Urol. 2018


Clinical and prognostic significance of changes in haemoglobin concentration during 1 year of androgen-deprivation therapy for hormone-naïve bone-metastatic prostate cancer.

Ebbinge M, Berglund A, Varenhorst E, Hedlund PO, Sandblom G; Scandinavian Prostate Cancer Group (SPCG)-5 Study Group.

BJU Int. 2018


To help you in your daily work, the SPCG welcomes you to our website for further information. You may find important news from the SPCG, updated results of our protocols, abstracts from meetings, information about forthcoming meetings and published clinical research. Important links to other pages related to prostate cancer are included. We hope you will find these pages useful and informative.